Mazdutide 10mg

What is Mazdutide?

Mazdutide (formerly known as IBI362) is an experimental GLP-1 and glucagon receptor agonist for  weight loss and type 2 diabetes treatment.

Like tirzepatide (Mounjaro) and retatrutide, mazdutide is part of the new generation of multi-receptor weight-loss drugs.

How Does Mazdutide Work?

Mazdutide activates two key receptors:

1. GLP-1 (Glucagon-like peptide-1) receptor – Reduces appetite, slows digestion, and helps with blood sugar control.
2. Glucagon receptor – Increases energy expenditure and fat burning.

It does not activate the GIP receptor, unlike tirzepatide and retatrutide.

Effectiveness in Clinical Trials

• In Phase 2 trials, patients on 9 mg mazdutide lost an average of 15.4% of their body weight over 48 weeks.
• Blood sugar levels and cholesterol also improved significantly.
• The weight loss effect is similar to semaglutide (Wegovy, Ozempic) but less than tirzepatide (Mounjaro) or retatrutide.